How CBD Works With Your Body’s Endocannabinoid System

What is CBD?

CBD (Cannabidiol) is a natural ingredient found in cannabis plants, known as a phytocannabinoid. CBD was discovered in 1940 and is growing as a popular food supplement to promote mental and physical wellbeing. CBD is non-psychoactive, non-addictive, and cannot get you high. Our CBD products are made from hemp and contain 0% THC, making them entirely safe and legal. CBD offers many fantastic health benefits without side effects, supporting general health and wellness alongside a balanced diet and lifestyle. CBD is one of the most naturally beneficial supplements you can take.

What is the Endocannabinoid System?

The Endocannabinoid System (ECS), discovered in 1988, is found throughout our own nervous system, immune system, and major organs, to help maintain balance in our body. It regulates pain, mood, inflammation, memory, sleep, hormones, and digestion to support overall wellbeing.

Our body produces the feel-good endocannabinoid, anandamide (AEA), and this can also be stimulated by dark chocolate, truffles, and CBD oil.

Why do we need CBD?

If our body becomes unbalanced or something disrupts this balance such as an injury, disease or deficiency, the ECS shifts from regulating wellbeing to restoring balance and normal functions. However, sometimes the ECS doesn’t work perfectly and lacks endocannabinoids. Adding phytocannabinoids such as CBD can help support the ECS.

How does the Endocannabinoid System Work?

The Endocannabinoid System consists of three key components:

1. Endocannabinoids

These neurotransmitters, produced by our body, become active when they bind to CB1 or CB2 receptors to keep bodily functions running smoothly. Anandamide (AEA) and 2-Arachidonoy lGlycerol (2-AG) are endocannabinoids which are structurally similar to phytocannabinoids such as Cannabidiol (CBD).

2. Cannabinoid Receptors

CB1 and CB2 receptors are found throughout the body and they activate endocannabinoids to send messages to the ECS to carry out a response. CB1 receptors are mainly located in the Central Nervous System, and CB2 receptors are most abundant in the Immune System and Peripheral Tissues.

3. Enzymes

These produce Endocannabinoids and break them down after they carry out the needed response and functions. The main enzymes involved are Fatty Acid Amide Hydrolase (FAAH) and Monoacylglycerol lipase (MAGL).

Phytocannabinoids (CBD) found in plants resemble our body’s own endocannabinoids, making them safe and familiar, and able to interact with our own cannabinoid receptors. CBD helps by preventing enzymes from breaking down endocannabinoids too early, enhancing their positive effects and promoting overall wellbeing and balance within the body.

FAQs?

1. Is CBD psychoactive? Will it get you high?

Metainoia CBD is not psychoactive because our CBD contains 0% THC, and we have the certificate of analysis reports to prove it.

THC (Tetrahydrocannabinol) is the intoxicating, psychoactive chemical responsible for the ‘high’ associated with marijuana. Since our products are free from THC, CBN (Cannabinol), and THCV (Tetrahydrocannabivarin), it cannot get you ‘high’.
2. Is CBD safe to use? Are there any potential side effects? Is CBD addictive?

The World Health Organisation in 2018 stated that “CBD is generally well tolerated with a good safety profile” In rare cases, some people may experience relatively mild side effects such as diarrhoea or fatigue. However, issues with side effects from CBD most frequently come from very high doses of CBD, combining CBD with other medications, or using CBD alongside other health conditions. Since Metanoia CBD is produced by a regulated manufacturer, and as long as it only used as directed on the label, it is completely safe. It is not addictive, and it does not induce psychological or physical dependencies or withdrawals. However, it is advisable to consult with a healthcare professional before using CBD, particularly if you have underlying health conditions or are taking medications.
3. How do I take Metanoia CBD Oil?

Shake your spray bottle before use to ensure that the ingredients are well-mixed. Lift your tongue and aim the spray nozzle under your tongue. Once you spray under your tongue (sublingually), hold it for 30 to 90 seconds to give enough time for the CBD to be absorbed. Underneath your tongue is the oral mucous membrane, which has a dense supply of blood vessels. Since the oral membrane is thin and permeable, CBD can be absorbed directly into the bloodstream, without going through the digestive system first.
4. What are the benefits of an oil spray rather than a dropper?

Some may find an oral spray easier to use, more convenient, less fragile, allow for on-the-go-use, and they are more hygienic than oil droppers/pipettes. As well as this, each spray has a precise and consistent dosage (8mg/16mg/32mg) every time, eliminating the need for measuring or counting drops. We offer both options.
5. Is CBD legal in the UK?

Yes, our CBD is 100% legal in the UK! As an industry there are a lot of uncertainties because of its affiliation with cannabis. As long as there is less than 0.2% THC (tetrahydrocannabinol) in the whole CBD product, it is legal and will not test positive on a workplace drug test. We pride ourselves on having 0.0% THC, so you can rest assured our CBD is pure.
6. What is the best CBD oil dosage?

There is no exact dosage that should be taken because all our bodies are unique, and individual reactions to CBD can vary greatly from person to person. Since there is no such thing as a one-size-fits-all dosing recommendation, we recommend you start low and slow with just a couple of sprays daily, and then increase gradually until you find the dose which works for you.

It’s important to remember is that it takes time – CBD is personal to you and your needs and will require a trial-and-error approach before you find your desired dose and effects. Research suggests that the average CBD dosage is 20-40mg and the FDA recommends no more than 70mg a day. We recommend keeping detailed records of your CBD usage and observations in order to make informed decisions about dosage.
7. How and when do you take CBD oil?

Customers who seem to get the most out of CBD oil make it part of their morning routine or take it right before going to bed. The majority of our customers will split their dosage into 2-3 servings throughout the day (for example, morning, afternoon, and evening). Consistency is key! CBD is not a temporary solution to an immediate problem; the beauty of CBD is how it contributes to your body’s network which ensures you’re in a state of balance. Many people need to build up the substance in their system in order to start seeing benefits.
8. How long does it take for CBD to be absorbed and start working?

CBD affects everyone differently. It’s a step-by-step approach that acknowledges how the benefits of CBD, and how long it takes to achieve them, may differ from different delivery methods and the issue at hand. Often, people feel effects within 20 minutes, whereas others say this can take up to 1 hour. In many cases, you might need to take CBD as part of your daily routine over a few weeks to experience the full benefits.
9. How long does CBD stay in my system?

CBD sprays and drops have a half-life of 1 to 11 hours. Half-life is how long the body takes to eliminate one-half of a substance. Typically, the body will eliminate a drug within four to five half-lives. This means that CBD sprays can stay in the body for 10 hours to about 2 days. As with most other substances, the higher the dose you take, the longer CBD will stay in your system. The frequency of your usage also determines how long CBD stays in your body, as CBD builds up in your body over time if used regularly. If you use it only occasionally, it’ll clear from your system faster. Everyone’s body is different, so CBD and other substances affect people differently. Your body mass index, water content, and metabolism are only some of the things that can influence how long CBD stays in your system.
10. Who can take Metanoia CBD?
11. What are the storage guidelines for Metanoia CBD?
12. What is the difference between full-spectrum and broad-spectrum CBD oil?

Broad-spectrum CBD oil is a legal high-quality refined extract containing many valuable compounds found in the plant. It is essentially the same as full-spectrum however it has been refined further to remove THC, CBN and THCV (controlled drugs with intoxicating properties). Full-spectrum CBD is the most effective type of oil; however, it is illegal in the UK if there is more than 0.2% of controlled substances such as THC, CBD and THCV contained in it, and consumers can fail a controlled drug test.
13. Why should I choose Metanoia CBD products over other brands?
14. Are all CBD oils the same?

No, not all CBD oils are the same. There can be variations in the quality, potency, and composition of CBD oils, depending on various factors such as the extraction method, source of hemp, and manufacturing processes. You can trust that Metanoia CBD oils are derived from high-quality, organic hemp.

CBD oils can have different concentrations of CBD, so it’s essential to read the product label and follow the recommended dosage instructions provided by the manufacturer. We offer 1000mg (10mg per spray), 2000mg (20mg per spray), and 3000mg (30mg per spray) CBD in 10mg bottles.
15. How is CBD oil made?

Our hemp plants are harvested when they have reached their peak CBD content. The CBD is then extracted from the hemp plant using CO2 extraction. This efficient and clean method uses carbon dioxide under high pressure and low temperatures to isolate CBD from the plant material. The CBD is then diluted with coconut oil, a carrier oil, to create the final CBD oil product. This carrier oil not only helps with the administration and absorption of CBD but also provides additional nutritional benefits.
16. What is the difference between % and mg strength for CBD oils?

When it comes to CBD oils, the percentage (%), and milligram (mg) strength both refer to the concentration of CBD in the product, but they represent it in different ways.

The percentage indicates the proportion of CBD in relation to the total volume of the oil. For example, if a CBD oil bottle says it has a 10% concentration, it means 10% of the total volume is CBD. So, in a 10ml bottler, there would be 1000mg of CBD.

On the other hand, milligram (mg) strength specifies the exact amount of CBD contained in the product. It measures the total amount of CBD per serving, regardless of the oil’s volume. For instance, a 10ml bottle labelled as 2000mg of CBD means that the entire bottle contains 2000mg of CBD.